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Keiichi Koizumi Selected Research

Chemokine CXCL16

12/2014CXCL16 suppresses liver metastasis of colorectal cancer by promoting TNF-α-induced apoptosis by tumor-associated macrophages.
3/2013Chemokine CXCL16 suppresses liver metastasis of colorectal cancer via augmentation of tumor-infiltrating natural killer T cells in a murine model.
11/2007Chemokine receptors in cancer metastasis and cancer cell-derived chemokines in host immune response.
5/2007High-level expression of chemokine CXCL16 by tumor cells correlates with a good prognosis and increased tumor-infiltrating lymphocytes in colorectal cancer.

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Keiichi Koizumi Research Topics

Disease

43Neoplasms (Cancer)
01/2022 - 12/2002
24Neoplasm Metastasis (Metastasis)
12/2014 - 12/2002
6Prostatic Neoplasms (Prostate Cancer)
03/2009 - 10/2004
6Carcinoma (Carcinomatosis)
05/2008 - 12/2002
5Hypoxia (Hypoxemia)
02/2022 - 01/2011
5Lung Neoplasms (Lung Cancer)
03/2015 - 01/2004
5Colorectal Neoplasms (Colorectal Cancer)
12/2014 - 05/2007
5Melanoma (Melanoma, Malignant)
07/2008 - 01/2003
3Metabolic Syndrome (Dysmetabolic Syndrome X)
01/2021 - 01/2019
3Dilated Cardiomyopathy (Cardiomyopathy, Congestive)
12/2018 - 01/2017
3Inflammation (Inflammations)
04/2015 - 09/2003
3Lymphatic Metastasis
01/2012 - 01/2004
3Peritoneal Neoplasms
01/2012 - 02/2006
2Breast Neoplasms (Breast Cancer)
03/2019 - 10/2013
2Mucocutaneous Lymph Node Syndrome (Kawasaki Disease)
02/2019 - 09/2018
2Wounds and Injuries (Trauma)
01/2018 - 01/2013
2Hypersensitivity (Allergy)
04/2015 - 11/2004
2Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
03/2015 - 06/2007
2Stomach Neoplasms (Stomach Cancer)
01/2012 - 05/2008
2Rheumatoid Arthritis
12/2008 - 10/2007
1Pancytopenia
02/2022
1Fever (Fevers)
02/2022
1Ventricular Heart Septal Defects (Ventricular Septal Defect)
02/2022
1Acidosis
02/2022
1Multiple Organ Failure (MODS)
02/2022
1Congenital Hypothyroidism (Cretinism)
02/2022
1Hyperthermia
02/2022
1Cytokine Release Syndrome
02/2022
1Down Syndrome (Down's Syndrome)
02/2022
1Cholecystitis
01/2022
1Pancreaticobiliary Maljunction
01/2022
1Body Weight (Weight, Body)
01/2020
1Ventricular Tachycardia
06/2018
1Shock
06/2018
1Ventricular Premature Complexes (Premature Ventricular Contraction)
06/2018
1Hemorrhage
09/2017
1Hypotension (Low Blood Pressure)
09/2017
1Fibrosis (Cirrhosis)
12/2016
1Lymphoma (Lymphomas)
12/2015

Drug/Important Bio-Agent (IBA)

11ChemokinesIBA
06/2015 - 01/2006
8LigandsIBA
10/2013 - 01/2006
6Chemokine ReceptorsIBA
06/2015 - 10/2006
5Biomarkers (Surrogate Marker)IBA
01/2021 - 06/2005
5Pharmaceutical PreparationsIBA
03/2019 - 01/2003
5Proteins (Proteins, Gene)FDA Link
01/2018 - 06/2005
4Messenger RNA (mRNA)IBA
01/2018 - 06/2005
4Chemokine CXCL16IBA
12/2014 - 05/2007
4Biological ProductsIBA
01/2013 - 06/2007
4Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
07/2010 - 12/2005
3Phosphotransferases (Kinase)IBA
07/2015 - 02/2006
3Chemokine CX3CL1IBA
06/2015 - 12/2009
3Chemotactic FactorsIBA
03/2013 - 09/2009
3keishibukuryoganIBA
12/2008 - 06/2007
3Matrix Metalloproteinases (MMPs)IBA
05/2008 - 12/2002
2Interleukin-6 (Interleukin 6)IBA
02/2022 - 06/2005
2bofu-tsusho-sanIBA
01/2021 - 01/2020
2Blood Glucose (Blood Sugar)IBA
01/2020 - 06/2005
2shikoninIBA
03/2019 - 01/2018
2NF-kappa B (NF-kB)IBA
01/2018 - 07/2010
2AutoantibodiesIBA
09/2017 - 01/2017
2AntigensIBA
12/2015 - 01/2010
2Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
03/2015 - 07/2008
2Chemokine CXCL12IBA
01/2012 - 05/2008
2CXCR4 Receptors (CXCR4 Receptor)IBA
01/2012 - 11/2007
2hachimijiogan (TJ 7)IBA
01/2011 - 06/2005
2Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA
02/2009 - 07/2007
2CurcuminIBA
06/2007 - 01/2003
2CaspasesIBA
12/2006 - 02/2006
2Peptide Hydrolases (Proteases)FDA Link
11/2006 - 03/2005
2IntegrinsIBA
10/2006 - 10/2004
2Androgen Receptors (Androgen Receptor)IBA
10/2006 - 10/2004
2Fibronectins (Fibronectin)IBA
06/2006 - 03/2005
2ubenimexIBA
04/2006 - 12/2004
2AminopeptidasesIBA
04/2006 - 12/2004
2CGS 27023AIBA
01/2004 - 01/2003
2Matrix Metalloproteinase InhibitorsIBA
01/2004 - 01/2003
1Interleukin-10 (Interleukin 10)IBA
02/2022
1Thyroxine (Levothyroxine)FDA LinkGeneric
02/2022
1Transaminases (Aminotransferases)IBA
02/2022
1Furosemide (Lasix)FDA LinkGeneric
02/2022
1Acetaminophen (Paracetamol)FDA LinkGeneric
02/2022
1phytobacteriomycin (PBM)IBA
01/2022
1NAADP (nicotinic acid adenine dinucleotide phosphate)IBA
05/2021
1Adenosine Triphosphatases (ATPase)IBA
05/2021
1Focal Adhesion Protein-Tyrosine KinasesIBA
05/2021
1Infliximab (Remicade)FDA Link
09/2018
1Verapamil (Calan)FDA LinkGeneric
06/2018
1Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
01/2018
1Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA
01/2018
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
12/2016

Therapy/Procedure

10Therapeutics
01/2016 - 09/2003
8Kampo Medicine (Kampo)
01/2021 - 06/2005
5Oral Administration
01/2020 - 01/2003
4Plasma Exchange
02/2019 - 01/2017
1Operative Surgical Procedures
02/2022
1Perioperative Period
02/2022
1Induced Hyperthermia (Thermotherapy)
02/2022
1Laparoscopic Cholecystectomy
01/2022
1Implantable Defibrillators (Implantable Cardioverter-Defibrillator)
06/2018
1Blood Component Removal (Apheresis)
09/2017